mRNA vaccines

According to Der Spiegel, the mRNA vaccine development technology accelerated to deal with coronavirus could be adapted to protect against some forms of cancer and other diseases. In fact, some scientists working on these other diseases switched temporarily to coronavirus vaccine development, and will eventually go back to their regularly scheduled programming.

The trick is that each patient receives an mDNA that is precisely tailored to the genetic profile of the cancer they are suffering from. These personalized cancer immunotherapies are still considered experimental, but the results of the initial study were so promising that Türeci, Şahin and their team were able to publish their results in July 2017 in Nature, the prominent scientific magazine. Almost two years later, a 52-year-old skin cancer patient in the U.S. received the experimental BioNTech treatment, after which he told Nature: “I was actually witnessing the cancer cells shrinking before my eyes.”

Der Spiegel

If a massive investment can break a log jam that has stymied research progress into a particular problem for decades, why don’t we do it more often? It would seem to support one of our most competitive industries, create jobs and stimulate the economy in the short term, and I would imagine it has a long term economic payoff. It would be nice to have an HIV vaccine and a male contraceptive shot or pill, just to name a couple.

Since this is publicly funded, will the “recipe” be made available to the WHO or other countries’ health agencies for free. That would seem like the moral thing to do. I also wonder though if the technology could be put to nefarious purposes like biological warfare or terrorism.

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