Tag Archives: covid-19

May 2022 in Review

Most frightening and/or depressing story: The lab leak hypothesis is back, baby! Whether Covid-19 was or was not a lab accident, the technology for accidental or intentional release of engineered plagues has clearly arrived. And also, the world is waking up to a serious food crisis.

Most hopeful story: I came up with (but I am sure I didn’t think of it first) the idea of a 21st century bill of rights. This seems to me like a political big idea somebody could run with. I’ll expand on it at some point, but quick ideas would be to clarify that the right to completely free political speech applies to human beings only and put some bounds on what it means for corporations and other legal entities, and update the 18th century idea of “unlawful search and seizure” to address the privacy/security tradeoffs of our modern world. And there’s that weird “right to bear arms” thing. Instead of arguing about what those words meant in the 18th century, we could figure out what we want them to mean now and then say it clearly. For example, we might decide that people have a right to be free of violence and protected from violence, in return for giving up any right to perpetrate violence. We could figure out if we think people have a right to a minimum standard of living, or housing, or health care, or education. And maybe clean up the voting mess?

Most interesting story, that was not particularly frightening or hopeful, or perhaps was a mixture of both: I found one easily accessible and understandable source of Covid-19 wastewater surveillance data.

the lab leak hypothesis

Deconstructed podcast says the idea that Covid-19 may have originated in an unintentional leak from a Wuhan virology lab is looking “stronger by the day”. There is no smoking gun proving it, but nor is this a conspiracy theory. The facts appear to be that the science and technology to modify a natural coronavirus into something more transmissable and deadly exists, and that this type of research was being carried out at the Wuhan lab in question.

To me, the fact that there was a lab conducting this type of research near where the novel virus was first detected does not prove that it was the source. I would want to know how many labs around the world are conducting this type of research. In other words, do many cities around the world have labs conducting this type of research? If so, the fact that there was a lab in the city where Covid-19 was first detected would be expected and likely, and not evidence that it was the source. But if there are labs all over the place doing this type of research, would that be comforting in any way? Certainly no!

I am a little surprised there are not more conspiracy theories suggesting any of the variants could be genetically modified. It seems like the technology would exist for some sociopathic scientist to take a sample of the virus and mess with it. Let’s hope that is not happening. But even if there is no suggestion it is happening now, this sort of thing is going to happen. It seems like a big risk to me – how do we deal with it?

other diseases to think about

Are you sick and tired of worrying about Covid-19? You may feel better if you take a step back and realize it is just one of many horrible and exotic (not to mention horrible and common) diseases you can be terrified of.

A couple of hantavirus cases have popped up, spread by rats in Washington D.C. The article mentions Baltimore as another rat capital. Luckily it doesn’t mention Philadelphia so there is nothing to worry about, although I see them frequently around my neighborhood due to the completely inept trash pickup practices in our city. I also see them frequently around construction sites and occasionally in parks. I have never seen one indoors but we see plenty of their less terrifying cousins the mice, which also can spread hantavirus. The article describes one person who contracted hantavirus, is a plumber’s assistant, and does not believe he could have been exposed through his work. Well, have a look behind the walls in an old house in any of the cities mentioned above and you will see plenty of evidence of rodent activity. Apparently he is okay and I wish him well.

This is also concerning:

According to DLD Director-General Sorawit Thanito, the World Organization for Animal Health (OIE) recorded outbreaks of avian influenza at 5,213 locations in 61 countries for 2021. A recent OIE article published on February 25, 2022, reported outbreaks of Highly Pathogenic Avian Influenza (HPAI) H5N1 H5N6 H5N2 H5N5, and H5N8 viruses in more than 30 countries across Africa, America, Europe and Asia. The World Health Organization (WHO) has meanwhile reported human infection cases and fatalities of H5N6 avian influenza in China.

Pattaya Mail

Nothing to worry about. The infected birds may be all over the world, and the 1918 flu may have been a bird flu, but only some unknown number of human beings has been infected and killed so far. These people were far away, not U.S. citizens, and I can’t think of any recent cases of exotic fatal diseases that started in China and spread to the rest of the world, can you? At least we have had a bit of a dress rehearsal for a really bad flu outbreak.

new CDC mask guidance

In my coronavirus trackers and simulations revisited post, I have updated the CDC link o their new “COVID-19 by County” page based on guidance issued Friday, February 26 (it’s 2022 in case you are an anthropologist reading this thousands of years in the future.) The updated recommendation is to mask indoors if new cases in your county are 200,000 per 100,000 population per week, AND if the number of people entering the hospital and/or in the hospital is above certain thresholds. It’s a little hard to find the data and figure out yourself, so if you trust the CDC (and who wouldn’t?) you can just type in your county and they will tell you if it is high/medium/low. My home county of Philadelphia is in the medium category, indicating we don’t need to mask indoors, but the city will be slow to react and the school district will be even slower if they react at all.

flu and Parkinson’s

This article makes a link between flu infection and increased risk of developing Parkinson’s disease later in life. It makes me wonder if a person’s history with viruses and other infections has a more significant effect on the brain than the average person things. There has been so much talk and worry about the effects of Covid-19 on the brain, but I wonder if a lot of viruses have these effects and Covid-19 is just the one we happen to have studied incredibly intensively over the past 2 years. It’s a disturbing thought, but also suggests that vaccines for certain viruses earlier in life could reduce risk of developing dementia later in life.

2021: Year in Review

As per usual, I’ll list out and link to the stories I chose as the most frightening, most hopeful, and most interesting each month in 2021. Then I’ll see if I have anything smart to say about how it all fits together.

Survey of the Year’s Stories and Themes

Most frightening and/or depressing stories:

  • JANUARY: A China-Taiwan military conflict is a potential start-of-World-War-III scenario. This could happen today, or this year, or never. Let’s hope for the latter. This is a near-term existential risk, but I have to break my own “rule of one” and give honorable mention to two longer-term scary things: crashing sperm counts and the climate change/fascism/genocide nexus.
  • FEBRUARY: For people who just don’t care that much about plants and animals, the elevator pitch on climate change is it is coming for our houses and it is coming for our food and water.
  • MARCH: In the U.S. upper Midwest (I don’t know if this region is better or worse than the country as a whole, or why they picked it), electric blackouts average 92 minutes per year, versus 4 minutes per year in Japan.
  • APRIL: One of the National Intelligence Council’s scenarios for 2040 involves “far-reaching changes designed to address climate change, resource depletion, and poverty following a global food catastrophe caused by climate events and environmental degradation”.
  • MAY: The Colorado River basin is drying out.
  • JUNE: For every 2 people who died of Covid-19 in the U.S. about 1 additional person died of indirect effects, such as our lack of a functioning health care system and safe streets compared to virtually all our peer countries.
  • JULY: The western-U.S. megadrought looks like it is settling in for the long haul.
  • AUGUST: The U.S. is not prepared for megadisasters. Pandemics, just to cite one example. War and climate change tipping points, just to cite two others. Solutions or at least risk mitigation measures exist, such as getting a health care system, joining the worldwide effort to deal with carbon emissions, and as for war, how about just try to avoid it?
  • SEPTEMBER: The most frightening climate change tipping points may not be the ones we hear the most about in the media (at least in my case, I was most aware of melting ice sheets in Greenland and Antarctica, collapse of ocean circulation patterns). The most damaging may be melting permafrost on land and methane hydrates underwater, both of which contain enormous amounts of methane which could set off a catastrophic and unstoppable feedback loop if released in large quantities.
  • OCTOBER: The technology (sometimes called “gain of function“) to make something like Covid-19 or something much worse in a laboratory clearly exists right now, and barriers to doing that are much lower than other types of weapons. Also, because I just couldn’t choose this month, asteroids can sneak up on us.
  • NOVEMBER: Freakonomics podcast explained that there is a strong connection between cars and violence in the United States. Because cars kill and injure people on a massive scale, they led to an expansion of police power. Police and ordinary citizens started coming into contact much more often than they had. We have no national ID system so the poor and disadvantaged often have no ID when they get stopped. Everyone has guns and everyone is jumpy. Known solutions (safe street design) and near term solutions (computer-controlled vehicles?) exist, but are we going to pursue them as a society? I guess I am feeling frightened and/or depressed today, hence my choice of category here.
  • DECEMBER: Mass migration driven by climate change-triggered disasters could be the emerging big issue for 2022 and beyond. Geopolitical instability is a likely result, not to mention enormous human suffering.

Most hopeful stories:

  • JANUARY: Computer modeling, done well, can inform decisions better than data analysis alone. An obvious statement? Well, maybe to some but it is disputed every day by others, especially staff at some government regulatory agencies I interact with.
  • FEBRUARY: It is possible that mRNA technology could cure or prevent herpes, malaria, flu, sickle cell anemia, cancer, HIV, Zika and Ebola (and obviously coronavirus). With flu and coronavirus, it may become possible to design a single shot that would protect against thousands of strains. It could also be used for nefarious purposes, and to protect against that are ideas about what a biological threat surveillance system could look like.
  • MARCH: I officially released my infrastructure plan for America, a few weeks before Joe Biden released his. None of the Sunday morning talk shows has called me to discuss so far. Unfortunately, I do not have the resources of the U.S. Treasury or Federal Reserve available to me. Of course, neither does he unless he can convince Congress to go along with at least some portion of his plans. Looking at his proposal, I think he is proposing to direct the fire hoses at the right fires (children, education, research, water, the electric grid and electric vehicles, maintenance of highways and roads, housing, and ecosystems. There is still no real planning involved, because planning needs to be done in between crises and it never is. Still, I think it is a good proposal that will pay off economically while helping real people, and I hope a substantial portion of it survives.
  • APRIL: Giant tortoises reach a state of “negligible senescense” where they simply don’t age for a long time. Humans are distant relatives of giant tortoises, so maybe we can aspire to this some day. They are not invulnerable to injury and disease.
  • MAY: An effective vaccine for malaria may be on the way. Malaria kills more children in Africa every year than Covid-19 killed people of all ages in Africa during the worst year of the pandemic. And malaria has been killing children every year for centuries and will continue long after Covid-19 is gone unless something is done.
  • JUNE: Masks, ventilation, and filtration work pretty well to prevent Covid transmission in schools. We should learn something from this and start designing much healthier schools and offices going forward. Design good ventilation and filtration into all buildings with lots of people in them. We will be healthier all the time and readier for the next pandemic. Then masks can be slapped on as a last layer of defense. Enough with the plexiglass, it’s just stupid and it’s time for it to go.
  • JULY: A new Lyme disease vaccine may be on the horizon (if you’re a human – if you are a dog, talk to your owner about getting the approved vaccine today.) I admit, I had to stretch a bit to find a positive story this month.
  • AUGUST: The Nordic welfare model works by providing excellent benefits to the middle class, which builds the public and political support to collect sufficient taxes to provide the benefits, and so on in a virtuous cycle. This is not a hopeful story for the U.S., where wealthy and powerful interests easily break the cycle with anti-tax propaganda, which ensure benefits are underfunded, inadequate, available only to the poor, and resented by middle class tax payers.
  • SEPTEMBER: Space-based solar power could finally be in our realistic near-term future. I would probably put this in the “interesting” rather than “hopeful” category most months, but I really struggled to come up with a hopeful story this month. I am at least a tiny bit hopeful this could be the “killer app” that gets humanity over the “dirty and scarce” energy hump once and for all, and lets us move on to the next layer of problems.
  • OCTOBER: The situation with fish and overfishing is actually much better than I thought.
  • NOVEMBER: Urban areas may have some ecological value after all.
  • DECEMBER: Covid-19 seems to be “disappearing” in Japan, or at least was before the Omicron wave. Maybe lessons could be learned. It seems possible that East Asian people have at least some genetic defenses over what other ethnic groups have, but I would put my money on tight border screening and an excellent public health care system. Okay, now I’m starting to feel a bit depressed again, sitting here in the U.S. where we can’t have these nice things thanks to our ignorant politicians.

Most interesting stories, that were not particularly frightening or hopeful, or perhaps were a mixture of both:

  • JANUARY: There have been fabulous advances in note taking techniques! Well, not really, but there are some time honored techniques out there that could be new and beneficial for many people to learn, and I think this is an underappreciated productivity and innovation skill that could benefit people in a lot of areas, not just students.
  • FEBRUARY: At least one serious scientist is arguing that Oumuamua was only the tip of an iceberg of extraterrestrial objects we should expect to see going forward.
  • MARCH: One study says 1-2 days per week is a sweet spot for working from home in terms of a positive economic contribution at the national scale. I think it is about right psychologically for many people too. However, this was a very theoretical simulation, and other studies attempting to measure this at the individual or firm scale have come up with a 20-50% loss in productivity. I think the jury is still out on this one, but I know from personal experience that people need to interact and communicate regularly for teams to be productive, and some people require more supervision than others, and I don’t think technology is a perfect substitute for doing these things in person so far.
  • APRIL: Hydrogen fuel cells may finally be arriving. Not so much in the U.S., where we can’t have nice things.
  • MAY: I learned about Lawrence Kohlberg, who had some ideas on the use of moral dilemmas in education.
  • JUNE: The big U.S. government UFO report was a dud. But what’s interesting about it is that we have all quietly seemed to have accepted that something is going on, even if we have no idea what it is, and this is new.
  • JULY: “Cliodynamics” is an attempt at a structured, evidence-based way to test hypotheses about history.
  • AUGUST: Ectogenesis is an idea for colonizing other planets that involves freezing embryos and putting them on a spaceship along with robots to thaw them out and raise them. Fungi could also be very useful in space, providing food, medicine, and building materials.
  • SEPTEMBER: Philip K. Dick was not only a prolific science fiction author, he also developed a comprehensive theory of religion which could possibly even be the right one. Also, possibly related but not really, if there are aliens out there they might live in creepy colonies or super-organisms like ants or termites.
  • OCTOBER: I thought about how to accelerate scientific progress: “[F]irst a round of automated numerical/computational experiments on a huge number of permutations, then a round of automated physical experiments on a subset of promising alternatives, then rounds of human-guided and/or human-performed experiments on additional subsets until you hone in on a new solution… [C]ommit resources and brains to making additional passes through the dustbin of rejected results periodically…” and finally “educating the next generation of brains now so they are online 20 years from now when you need them to take over.” Easy, right?
  • NOVEMBER: Peter Turchin continues his project to empirically test history. In this article, he says the evidence points to innovation in military technologies being driven by “world population size, connectivity between geographical areas of innovation and adoption, and critical enabling technological advances, such as iron metallurgy and horse riding“. What does not drive innovation? “state-level factors such as polity population, territorial size, or governance sophistication“. As far as the technologies coming down the pike in 2022, one “horizon scan” has identified “satellite megaconstellations, deep sea mining, floating photovoltaics, long-distance wireless energy, and ammonia as a fuel source”.
  • DECEMBER: Time reminded us of all the industries Elon Musk has disrupted so far: human-controlled, internal-combustion-fueled automobiles; spaceflight; infrastructure construction (I don’t know that he has really achieved any paradigm shifts here, but not for lack of trying), “artificial intelligence, neurotechnology, payment systems and cryptocurrency.” I’m not sure I follow a couple of these, but I think they missed satellites.

Continuing Signs of U.S. Relative Decline

Signs of U.S. decline relative to our peer group of advanced nations are all around us. I don’t know that we are in absolute decline, but I think we are now below average among the most advanced countries in the world. We are not investing in the infrastructure needed in a modern economy just to reduce friction and let the economy function. The annual length of electric blackouts in the U.S. (hours) compared to leading peers like Japan (minutes) is just one telling indicator. In March, I looked at the Build Back Better proposal and concluded that it was more like directing a firehose of money at a range of problems than an actual plan, but I hoped at least some of it would happen. My rather low but not zero expectations were met, as some limited funding was provided for “hard infrastructure” and energy/emissions projects, but little or nothing (so far, as I write this) to address our systemic failures in health care, child care, or education. The crazy violence on our streets, both gun-related and motor vehicle-related, is another indicator. Known solutions to all these problems exist and are being implemented to various extents by peer countries. Meanwhile our toxic politics and general ignorance continue to hold us back. Biden really gave it his best shot – but if this is our “once in a generation” attempt, we are headed down a road where we will no longer qualify as a member of the pack of elite countries, let alone its leader.

The Climate Change, Drought, Food, Natural Disaster, Migration and Geopolitical Instability Nexus

2021 was a pretty bad year for storms, fires, floods, and droughts. All these things affect our homes, our infrastructure, our food supply, and our water supply. Drought in particular can trigger mass migration. Mass migration can be a disaster for human rights and human dignity in and of itself, and managing it effectively is difficult even for well-intentioned governments. But an insidious related problem is that migration pressure can tend to fuel right wing populist and racist political movements. We see this happening all over the world, and the situation seems likely to get worse.

Tipping Points and other Really Bad Things We Aren’t Prepared For

We can be thankful that nothing really big and new and bad happened in 2021. My apologies to anyone reading this who lost someone or had a tough year. Of course, plenty of bad things happened to good people, and plenty of bad things happened on a regional or local scale. But while Covid-19 ground on and plenty of local and regional-scale natural disasters and conflicts occurred, there were no new planetary-scale disasters. This is good because humanity has had enough trouble dealing with Covid-19, and another major disaster hitting at the same time could be the one that brings our civilization to the breaking point.

So we have a trend of food insecurity and migration pressure creeping up on us over time, and we are not handling it well even given time to do so. Maybe we can hope that some adjustments will be made there to get the world on a sustainable track. Even if we do that, there are some really bad things that could happen suddenly. Catastrophic war is an obvious one. A truly catastrophic pandemic is another (as opposed to the moderately disastrous pandemic we have just gone through.) Creeping loss of human fertility is one that is not getting much attention, but this seems like an existential risk if it were to cross some threshold where suddenly the global population starts to drop quickly and we can’t do anything about it. Asteroids were one thing I really thought we didn’t have to worry much about on the time scale of any human alive today, but I may have been wrong about that. And finally, the most horrifying risk to me in the list above is the idea of an accelerating, runaway feedback loop of methane release from thawing permafrost or underwater methane hydrates.

We are almost certainly not managing these risks. These risks are probably not 100% avoidable, but since they are existential we should be actively working to minimize the chance of them happening, preparing to respond in real time, and preparing to recover afterward if they happen. Covid-19 was a dress rehearsal for dealing with a big global risk event, and humanity mostly failed to prepare or respond effectively. We are lucky it was one we should be able to recover from as long as we get some time before the next body blow. We not only need to prepare for much, much worse events that could happen, we need to match our preparations to the likelihood of more than one of them happening at the same time or in quick succession.

Technological Progress

Enough doom and gloom. We humans are here, alive, and many of us are physically comfortable and have much more leisure time than our ancestors. Our social, economic, and technological systems seem to be muddling through from day to day for the time being. We have intelligence, science, creativity, and problem solving abilities available to us if we choose to make use of them. Let’s see what’s going on with technology.

Biotechnology: The new mRNA technology accelerated by the pandemic opens up potential cures for a range of diseases. We need an effective biological surveillance system akin to nuclear weapons inspections (which we also need) to make sure it is not misused (oops, doom and gloom trying to creep in, but there are some ideas for this.) We have vaccines on the horizon for diseases that have been plaguing us for decades or longer, like malaria and Lyme disease. Malaria kills more children worldwide, year in and year out, than coronavirus has killed per year at its peak.

Promising energy technologies: Space based solar power may finally be getting closer to reality. Ditto for hydrogen fuel cells in vehicles, although not particularly in the U.S. (I’m not sure this is preferable to electric vehicles for everyday transportation, but it seems like a cleaner alternative to diesel and jet fuel when large amounts of power are needed in trucking, construction, and aviation, for example.)

Other technologies: We are actually using technology to catch fish in more sustainable ways, and to grow fish on farms in more sustainable ways. We are getting better at looking for extraterrestrial objects, and the more we look, the more of them we expect to see (this one is exciting and scary at the same time). We are putting satellites in orbit on an unprecedented scale. We have computers, robots, artificial intelligence of a sort, and approaches to use them to potentially accelerate scientific advancements going forward.

The State of Earth’s Ecosystems

The state and trends of the Earth’s ecosystems continue to be concerning. Climate change continues to churn through the public consciousness and our political systems, and painful as the process is I think our civilization is slowly coming to a consensus that something is happening and something needs to be done about it (decades after we should have been able to do this based on the evidence and knowledge available.) When it comes to our ecosystems, however, I think we are in the very early stages of this process. This is something I would like to focus on in this blog in the coming year. My work and family life are busy, and I have decided to take on an additional challenge of becoming a student again for the first time in the 21st century, but somehow I will persevere. If you are reading this shortly after I write it in January 2022, here’s to good luck and prosperity in the new year!

December 2021 in Review

Most frightening and/or depressing story: Mass migration driven by climate change-triggered disasters could be the emerging big issue for 2022 and beyond. Geopolitical instability is a likely result, not to mention enormous human suffering.

Most hopeful story: Covid-19 seems to be “disappearing” in Japan, or at least was before the Omicron wave. Maybe lessons could be learned. It seems possible that East Asian people have at least some genetic defenses over what other ethnic groups have, but I would put my money on tight border screening and an excellent public health care system. Okay, now I’m starting to feel a bit depressed again, sitting here in the U.S. where we can’t have these nice things thanks to our ignorant politicians.

Most interesting story, that was not particularly frightening or hopeful, or perhaps was a mixture of both: Time reminded us of all the industries Elon Musk has disrupted so far: human-controlled, internal-combustion-fueled automobiles; spaceflight; infrastructure construction (I don’t know that he has really achieved any paradigm shifts here, but not for lack of trying), “artificial intelligence, neurotechnology, payment systems and cryptocurrency.” I’m not sure I follow a couple of these, but I think they missed satellites.

Longreads Best of 2021

(Too)Long(didn’t)reads.com picks a best article every week, and once a year they list all of them from the past year. I probably won’t have time to really dig into many of these, but there are certainly interesting topics here and they provide a look back on the year.

  • a look back at the January 6 attack on the US Congress by a fascist mob, just a few days after it happened
  • the story of the Covid vaccine development, and on a much less happy note, the Covid carnage in US prisons, and the crisis in India as it was happening
  • “Inside Xinjiang’s Prison State” – I think I may have actually read this. What is happening there meets the UN definition of genocide and must stop. A wrinkle is that its genesis came shortly after the 9/11 attacks and U.S. invasion of Afghanistan. Almost anything could be justified as part of the Global War on Terror at the time. Xinjiang is next door to Afghanistan, and is home to a Muslim ethnic group, and within that ethnic group a resistance/terrorist group formed which perpetrated attacks on the imperial capital. The parallels are surprising when you think about it. The Chinese approach is not acceptable, but did that make the American approach in Afghanistan any more acceptable?
  • Anti-Asian-American violence. I continue to be a bit puzzled by this. I am not questioning its reality, it just doesn’t seem to be happening in the places or to the Asian-Americans I cross paths with. I wonder if it is really new or something like shark attacks that happens periodically and the media suddenly picked up on and made a big deal of for awhile. People could also be reporting it more often now that they feel someone is listening and something might be done about it.
  • Salem, Massachusetts witch tourism

East Asian people may have genetic defenses against Covid-19

It’s somewhat taboo to suggest that ethnic groups might be genetically superior or inferior to others, but when it comes to susceptibility or resistance to specific diseases, we should be willing to acknowledge this possibility. Most countries in Asia seemed to manage the Covid emergency much better than most western countries. I thought from the beginning that much better health and quarantine systems at airports must be a big factor. Somewhat privacy-invasive contact tracing measures and a willingness to restrict movement seem to be other significant differences between west and east, and you can see these even in Australia and New Zealand which are still largely ethnically European (although I say lots of Asian faces on trips on Sydney). But even given that, it always seemed like there might be some genetic or lifestyle factors to explain the order-of-magnitude differences.

Studies have shown that more people in Asia have a defense enzyme called APOBEC3A that attacks RNA viruses, including the SARS-CoV-2 virus that causes COVID-19, when compared to people in Europe and Africa…

Some people may wonder if the self-extinction of the delta variant in Japan was caused by something special in the genetic make-up of Japanese people, but Inoue disagrees.

“I don’t think so,” he said. “People in East Asia, such as Koreans, are ethnically the same as Japanese. But I don’t know why this observation was made in Japan.”

Japan Times

The “self-extinction”, by the way, is the idea that once isolated from external influxes and exposed to a largely resistant population, the virus may have acquired mutations that have doomed it.

I understand why it is politically and culturally hard to do contact tracing and quarantine in the U.S., and nearly impossible to physically restrict movement. I still don’t understand why we can’t implement effective screening and quarantine procedures at our international airports when we have had a year and a half of emergency conditions now to get that done.